HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → Ethyl 4-(bromomethyl)-2-chlorobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Benzoic acid, 2-chloro-4-methyl-, ethyl ester | HCID 14459377 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | Ethyl 4-(bromomethyl)-2-chlorobenzoate | HCID 14459378 | — |
Reaction Steps
A mixture of ethyl 2-chloro-4-methylbenzoate (2.34 g, 0.0118 mol), N-bromosuccinimide (2.05 g, 0.0115 mol), and benzoyl peroxide (0.5 g) in carbon tetrachloride (50 ml) was heated under reflux for 90 minutes. The resulting solution was filtered and the solvent was evaporated off under reduced pressure to yield ethyl 4-(bromomethyl)-2-chlorobenzoate as a yellow crystalline solid having the following structural characteristics:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04837333 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-144559fac48f445fa7c30663345cfb4e |
| Source note | uspto-grants-1989_06 |