Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1904433Generated: October 31, 2026

Methyl iodide → 1-(3,5-Difluorobenzyl)-2-methylmercaptoimidazole-5-carboxylic acid

https://huagongshe.com/reaction/1904433

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium MethoxideHCID 10942334—
ReactantHCID 178524783HCID 178524783—
SolventMethanolHCID 887—
Product1-(3,5-Difluorobenzyl)-2-methylmercaptoimidazole-5-carboxylic acidHCID 14769734—

Reaction Steps

Reaction of 1-(3,5-difluorobenzyl)-2-mercaptoimidazole-5-carboxylic acid prepared as in Example 1 with methyl iodide and sodium methoxide in methanol by standard techniques yields 1-(3,5-diflurobenzyl)-2-methylmercaptoimidazole-5-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04837353
Source datasetuspto-grants-1989_06
ORD IDord-f801145cd9844fceb7835110a3d3b0df
Source noteuspto-grants-1989_06