HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[6-(Cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoic acid → 4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoic N,N-diphenylcarbamic anhydride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[6-(Cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoic acid | HCID 14708751 | — |
| Reactant | 4-[5-(2-cyclopentylacetamido)-1-ethylindol-3-ylmethyl]-3-methoxybenzoic N,N-diphenylcarbamic anhydride | HCID 86743119 | — |
| Product | 4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoic N,N-diphenylcarbamic anhydride | HCID 88397244 | 96% |
Reaction Steps
Using a procedure similar to part (f) of Example 4, but using 4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoic acid (N) instead of acid (J), there was obtained 4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoic N,N-diphenylcarbamic anhydride (K) as a pink solid (2.14 g, 96%); partial NMR: (80 MHz, DMSO-d6): 3.86(s, 3H, OCH3), 5.49(s, 2H, ArCH2N), 7.42(s, 10H, NArH), 9.69(s, 1H, CONH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04837235 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-3566c3decc944fc2a1ba0676b937469d |
| Source note | uspto-grants-1989_06 |