反应详情

Using a procedure similar to part (f) of Example 4, but using 4-[6-(2-cyclopentylacetamido)indol-1-ylmethyl]-3-methoxybenzoic acid (Q) instead of acid (J), there was obtained 4-[6-(2-cyclopentylacetamido)indol-1-ylmethyl]-3-methoxybenzoic N,N-diphenyl carbamic anhydride (O) as an off-white powder (1.4 g, 92%); partial NMR: (80 MHz, DMSO-d6): 3.98(s, 3H, OCH3) 5.30(s, 2H, NCH2Ar), 7.40(s, 10H, NArH), 9.69(s, 1H, CONH).