Sulfuric Acid → HCID 14577959, compound

Participants

Reaction Steps

Methyl vinyl ketone (7.7 g) was added dropwise under ice cooling to a solution composed of 11 g of resorcinol, 11.7 g of trimethyl orthoformate and 0.1 ml of conc. sulfuric acid. After the addition, the mixture was stirred at room temperature for 2 hours. The reaction mixture was neutralized with a saturated aqueous solution of sodium bicarbonate, and then extracted with ethyl acetate. The residue left after evaporation of the solvent as purified by column chromatography to give 12.5 g (yield 70%) of the desired product as colorless crystals (melting point 107°-108° C.).

Provenance & Evidence