Sodium borohydride → HCID 131715958, compound

Participants

Reaction Steps

1.2 g (4.15 mmoles) of 13 dissolved in 50 ml of methanol was reduced with sodium borohydride (0.1 g) at 0° C. for 20 minutes. The excess sodium borohydride was consumed by the addition of acetone. After addition of 25 ml of water the solution was neutralized with acetic acid and then extracted with methylene chloride. The organic extracts were evaporated to dryness to give 1.2 g (100%) of 14.

Provenance & Evidence