HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → 107812-70-4
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Diethyl 2-(chloromethyl)-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | HCID 3064723 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 107812-70-4 | HCID 3065370 | 66% |
Reaction Steps
A mixture of 2-chloromethyl-3,5-dicarboethoxy-4-(m-nitrophenyl)-6-methyl-1,4-dihydropyridine (6 g) and triphenylphosphine (4 g) in CH3CN (60 ml) is heated to reflux temperature for six hours, then it is evaporated in vacuum and the residue crystallized from EtOH to give 6.5 g of [6-methyl-3,5-dicarboethoxy-4-(m-nitrophenyl)-1,4-dihydropyridin-2-yl]methyltriphenylphosphonium chloride, m.p. 225°-227° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04839348 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-befc34aef853493a9e299ff1aa543004 |
| Source note | uspto-grants-1989_06 |