Sodium Hydroxide → HCID 86743137, compound

HRID 1904584Notes

Reaction equation

HRID 1904584 reaction equation
C([S:4][CH2:5][CH:6]([CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:7]([NH:9][N:10]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1)=[O:8])(=O)C.[OH-].[Na+]>>[N:10]1([NH:9][C:7](=[O:8])[CH:6]([CH2:5][SH:4])[CH2:17][C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 86743138HCID 86743138, compound

Product 1

HCID 86743137HCID 86743137, compoundYield 97.2%

Procedure

Using the procedure of Example 6, 2 g of the product of Example 7 and 62.8 ml of 0.1N sodium hydroxide were reacted to obtain after chromatography on silica (eluent:methylene chloride - methanol, 100-2), 1.7 g of the expected product melting at about 82° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-7caf59cd53e24bfea58b7f9bc138fb2c
Source dataset
uspto-grants-1989_06
Patent number
US04839358

Reaction notes

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