Sodium Hydroxide → HCID 53659923, compound

HRID 1904585Notes

Reaction equation

HRID 1904585 reaction equation
C([S:4][CH2:5][CH:6]([CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:7]([NH:9][N:10]1[CH2:14][CH2:13][CH2:12][CH2:11]1)=[O:8])(=O)C.[OH-].[Na+]>>[SH:4][CH2:5][CH:6]([CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:7]([NH:9][N:10]1[CH2:14][CH2:13][CH2:12][CH2:11]1)=[O:8]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 86743139HCID 86743139, compound

Product 1

HCID 53659923HCID 53659923, compoundYield 85.8%

Procedure

Using the procedure of Example 6, 0.77 g of the product of Example 9 and 26 ml of 0.1N sodium hydroxide were reacted to obtain after chromatography on silica (eluent:methylene chloride - methanol, 100-3), 0.57 g of the expected product melting at 93° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-fa7d0487fa44436b8884c3a491acefb3
Source dataset
uspto-grants-1989_06
Patent number
US04839358

Reaction notes

Loading…