Trifluoroacetic acid → HCID 70069385, compound

Participants

Reaction Steps

Under an inert atmosphere, 7.4 g of the product of Step A were cooled to -15° C. in 20 ml of methylene chloride and then 13 ml of trifluoroacetic acid were added dropwise. After allowing to return to ambient temperature and stirring for 2 hours, neutralizing with a saturated aqueous solution of sodium bicarbonate, extractin was done with ethyl acetate. The extracts were washed with salted water, dried and the solvents were eliminated under reduced pressure to obtain 3.6 g of the expected product melting at 78° C.

Provenance & Evidence