Methyl iodide → HCID 54479618, compound

HRID 1904643Notes

Reaction equation

HRID 1904643 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:13]=[C:14]([F:16])[CH:15]=1)[CH2:5][C:6]1[C:7](=[S:12])[NH:8][CH:9]=[CH:10][CH:11]=1.[CH3:17]I>CO>[F:16][C:14]1[CH:13]=[C:4]([CH:3]=[C:2]([F:1])[CH:15]=1)[CH2:5][C:6]1[C:7]([S:12][CH3:17])=[N:8][CH:9]=[CH:10][CH:11]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 20037861HCID 20037861, compound

Product 1

HCID 54479618HCID 54479618, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The reaction of 3-(3,5-difluorobenzyl)pyridine-2-thione, prepared in Example 10, with methyl iodide in methanol in the presence of base by standard techniques yields 3-(3,5-difluorobenzyl)-2-methylmercaptopyridine.

Sources & evidence

ORD record
ord-1299b81d6f0d40f2bcd22f8c47fa1a02
Source dataset
uspto-grants-1989_06
Patent number
US04839371

Reaction notes

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