Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chloride | HCID 312 | — |
| Reactant | 2-Chloro-N,N-dimethylethylamine | HCID 7901 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 9-amino-3,4-dihydroacridin-1(2H)-one | HCID 184361 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 13935120 | HCID 13935120 | — |
Reaction Steps
To a suspension of 9-amino-3,4-dihydroacridin-1-(2H)-one (10.0 g) in 100 ml of dimethylformamide was added a 50% suspension of sodium hydride in oil (2.9 g). To this was added 2-dimethylaminoethyl chloride (6.5 g). The mixture was heated to 60° C pot temperature for 2.5 hours, an additional 2.7 g of the chloride was added and this was heated for an additional 1 hour.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04839364 |
|---|
| Source dataset | uspto-grants-1989_06 |
|---|
| ORD ID | ord-3db2cfdf3d524f02b60acf86cb41652b |
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| Source note | uspto-grants-1989_06 |
|---|
