HCID 14068928, compound → HCID 14068938, compound

HRID 1904784Notes

Reaction equation

HRID 1904784 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]23[CH2:15][CH:14]2[C:13](=[O:16])[N:12]([CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[C:11]3=[O:22])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]23[CH2:15][CH:14]2[C:13](=[O:16])[N:12]([CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[C:11]3=[O:22])=[CH:8][CH:9]=1

Participants

4

Reactant 1

HCID 14068928HCID 14068928, compound

Product 1

HCID 14068938HCID 14068938, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Following the procedure of Example 3, a solution of 5.3 g of 1-(4-nitrophenyl)-3-n-pentyl-3-azabicyclo[3.1.0]hexane-2,4-dione in 150 ml of ethanol is hydrogenated in the presence of 0.25 g of 5% palladium on carbon and worked up, affording the title compound which melts at 113°-115° C. after recrystallisation from ethyl acetate/petroleum ether.

Sources & evidence

ORD record
ord-03cf616f8a18405ca6ef9b49de7a0348
Source dataset
uspto-grants-1989_06
Patent number
US04839379

Reaction notes

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