HCID 14068928, compound → HCID 14068941, compound

HRID 1904785Notes

Reaction equation

HRID 1904785 reaction equation
[CH2:1]([N:6]1[C:11](=[O:12])[CH:10]2[C:8]([C:13]3[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][CH:14]=3)([CH2:9]2)[C:7]1=[O:22])CCCC>C(O)C.[Pd]>[NH2:19][C:16]1[CH:15]=[CH:14][C:13]([C:8]23[CH2:9][CH:10]2[C:11](=[O:12])[N:6]([CH2:1][C:8]([CH3:10])([CH3:9])[CH3:7])[C:7]3=[O:22])=[CH:18][CH:17]=1

Participants

4

Reactant 1

HCID 14068928HCID 14068928, compound

Product 1

HCID 14068941HCID 14068941, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Following the procedure of Example 3, a solution of 0.85 g of 3-n-pentyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione in 30 ml of ethanol is hydrogenated in the presence of 0.1 g of 5% palladium on carbon and worked up, affording the title compound which melts at 140°-143° C. after recrystallisation from ether/petroleum ether.

Sources & evidence

ORD record
ord-94316980fd3248a19082236034f443e6
Source dataset
uspto-grants-1989_06
Patent number
US04839379

Reaction notes

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