HCID 20038046, compound → HCID 23365354, compound

HRID 1904786Notes

Reaction equation

HRID 1904786 reaction equation
[CH2:1]([N:8]1[C:13](=[O:14])[CH:12]2[C:10]([C:15]3[CH:20]=[CH:19][C:18]([N+:21]([O-])=O)=[CH:17][CH:16]=3)([CH2:11]2)[C:9]1=[O:24])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]>C(O)C.[Pd]>[NH2:21][C:18]1[CH:17]=[CH:16][C:15]([C:10]23[CH2:11][CH:12]2[C:13](=[O:14])[N:8]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7])[C:9]3=[O:24])=[CH:20][CH:19]=1

Participants

4

Reactant 1

HCID 20038046HCID 20038046, compound

Product 1

HCID 23365354HCID 23365354, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Following the procedure of Example3, a solution of 5 g of 3-n-heptyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione in 100 ml of ethanol is hydrogenated in the presence of 0.3 g of 5% palladium on carbon and worked up, affording the title compound which melts at 78°-79° C. after recrystallisation from ether/petroleum ether.

Sources & evidence

ORD record
ord-6129cd2f0c6043faad6ca69647533e28
Source dataset
uspto-grants-1989_06
Patent number
US04839379

Reaction notes

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