Daidzein → Daidzein

Participants

Reaction Steps

To a solution of 2-acetamido-4-(4-nitrophenyl)butyric acid (57.65 g) in hot 95% ethanol (1000 ml) add d-(+)-α-methylbenzylamine (25.2 g) in hot 95% ethanol (125 ml), cool the solution slowly and keep at room temperature 18 hours. Collect the solid and wash with cold 95% ethanol, and dry to give an orange-yellow solid. Recrystallize this solid from 95% ethanol treated with charcoal to give 2(S)-acetamido-4-(4-nitrophenyl)butyric acid, d-(+)-α-methylbenzyl amine salt [α]D26 =+45.6 (MeOH), m.p. 211°-213° C.

Provenance & Evidence