HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 451826, compound → 5'-Amino-2',5'-dideoxy-5-ethyluridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 451826 | HCID 451826 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | 5'-Amino-2',5'-dideoxy-5-ethyluridine | HCID 451828 | — |
Reaction Steps
5'-Azido-5-ethyl-2',5'-dideoxyuridine (300 mg) is dissolved in a mixture of water-methanol (1:1, 25 ml) and then hydrogen gas is introduced with 10% Pd/C at room temperature under 1 atmosphere for 2 hr, after which the mixture is filtered and the filtrate is evaporated to a foam (160 mg, 50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04841039 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-a7da23bd3eb94f569c91d6111c11f800 |
| Source note | uspto-grants-1989_06 |