HCID 14444213, compound → Uridine, 2',3'-dideoxy-5-ethyl-3'-iodo-

Participants

Reaction Conditions

Reaction Steps

A mixture of 5-ethyl-3'-Iodo-5'-O-trityl-2',3'-dideoxyuridine (1.73 g, 2.8 mmole) and 80% HAc (25 ml) is heated at 100° C. for 50 min. After heating, acetic acid is evacuated in vacuo to obtain an amorphous solid. Ether is added, the product is triturated, and the resulting yellowish solid is filtered for collection (350 mg). Another 250 mg is obtained from the filtrate after repeating the above procedure, m.p. 162°-164° C.

Provenance & Evidence