HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Chloride → 2-(1-Benzylazepan-4-yl)-4-[(3,4-dichlorophenyl)methyl]phthalazin-1(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Chloride | HCID 7503 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 20037009 | HCID 20037009 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-(1-Benzylazepan-4-yl)-4-[(3,4-dichlorophenyl)methyl]phthalazin-1(2H)-one | HCID 3066519 | — |
Reaction Steps
A solution of 3.28 grams (8.15 mmoles) of 4-(3,4-dichlorobenzyl)-2-(hexahydro-1H-azepin-4-yl)-1-(2H)-phthalazinone, 3.4 ml (29.5 mmol) of benzyl chloride and 9 ml (64.6 mmol) of triethylamine in 20 ml of dioxane were heated for 12 hours at 200° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04841047 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-87934ef8af854d30a3a769e46712a7a4 |
| Source note | uspto-grants-1989_06 |