HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 4',5,7-Triacetoxy-2-bromomethylisoflavone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 4',5,7-Triacetoxy-2-methylisoflavone | HCID 22164358 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 4',5,7-Triacetoxy-2-bromomethylisoflavone | HCID 15598730 | 72.1% |
Reaction Steps
A solution of 4',5,7-triacetoxy-2-methylisoflavone (5 g), benzoyl peroxide (0.3 g) and N-bromosuccinimide (3.9 g) in 300 ml carbon tetrachloride was heated under reflux for 12 hours, the solvent was distilled off under reduced pressure, water was added to the solid residue, the mixture was stirred well, and the crude product collected by filtration was recrystallized from a methanol/chloroform mixed solvent, affording 4.3 g of 4',5,7-triacetoxy-2-bromomethylisoflavone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04841077 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-f17453f6de854d85819db5fe3188a466 |
| Source note | uspto-grants-1989_06 |