Ammonia → HCID 15598736, compound

HRID 1905056Notes

Reaction equation

HRID 1905056 reaction equation
[OH:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][C:11]([OH:18])=[CH:12][C:13]=3[OH:17])[O:8][C:7]=2[C:19](OCC)=[O:20])=[CH:4][CH:3]=1.[NH3:26]>>[OH:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][C:11]([OH:18])=[CH:12][C:13]=3[OH:17])[O:8][C:7]=2[C:19]([NH2:26])=[O:20])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 14459364HCID 14459364, compound

Product 1

HCID 15598736HCID 15598736, compound

Procedure

A mixture of ethyl 4',5,7-trihydroxy-2-isoflavonecarboxylate (120 mg) and 28% ammonia (2 ml) was stirred at room temperature for three hours, water was distilled off under reduced pressure, and the solid residue was recrystallized from methanol, affording 65 mg of 4',5,7-trihydroxy-2-isoflavonecarboxamide.

Workup

  1. distillationwater was distilled off under reduced pressure
  2. customthe solid residue was recrystallized from methanol

Sources & evidence

ORD record
ord-0d545b61ad454155bab90569f386e97b
Source dataset
uspto-grants-1989_06
Patent number
US04841077

Reaction notes

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