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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 190511Generated: October 27, 2026

1,1,1-Trifluoro-2-(4-iodo-phenyl)-propan-2-ol → 2-(4-(1,1,1-Trifluoro-2-hydroxypropan-2-yl)phenyl)-8-(2-(trifluoromethyl)phenylsulfonyl)-2,8-diazaspiro[4.5]decan-1-one

https://huagongshe.com/reaction/190511

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1,1-Trifluoro-2-(4-iodo-phenyl)-propan-2-olHCID 15134939—
Reactant8-(2-Trifluoromethyl-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 59577926—
Reactant2-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)-8-(2-(trifluoromethyl)phenylsulfonyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 59577944—
Product2-(4-(1,1,1-Trifluoro-2-hydroxypropan-2-yl)phenyl)-8-(2-(trifluoromethyl)phenylsulfonyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 59578041—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-9ed24f217b7e4076be7c302007079671
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)