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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 190533Generated: October 27, 2026

Tetrahydrofuran → Tert-butyl 4-[3-(3,5-difluorophenyl)-1-hydroxy-2-nitropropyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

https://huagongshe.com/reaction/190533

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde, (A+-)-HCID 3644090—
Reactant1,3-Difluoro-5-(2-nitroethyl)benzeneHCID 55250753—
ProductTert-butyl 4-[3-(3,5-difluorophenyl)-1-hydroxy-2-nitropropyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylateHCID 72477974—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-da6542ed61f64202a10254f8113e22b4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)