3-Nitrobenzaldehyde → HCID 54394823, compound

Participants

Reaction Steps

3.38 g of 2-acetonyl-(4R,6R)-4,6-dimethyl-1,3,2-dioxaphosphorinane-2-oxide and 2.4 g of m-nitrobenzaldehyde were dissolved in 15 ml of benzene, and 0.5 ml of piperidine was added thereto. The mixture was refluxed for 5 hours. The reaction solution was subjected to silica gel chromatography (developer solution: ethyl acetate/methanol=9/1 (v/v), Rf value: 0.4) to obtain 1.78 g of desired 2-(1-acetyl-2-(3-nitrophenyl)ethenyl)-(4R,6R)-4,6-dimethyl-1,3,2-dioxaphosphorinane-2-oxide as a yellow viscous liquid.

Provenance & Evidence