HuagongsheHuagongshe Chemistry Print Report · For research reference only
Epichlorohydrin → 1-(2-Cyano-5-chlorophenoxy)-2,3-epoxypropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Epichlorohydrin | HCID 7835 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Chloro-2-hydroxybenzonitrile | HCID 3442789 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(2-Cyano-5-chlorophenoxy)-2,3-epoxypropane | HCID 14578680 | 75.7% |
Reaction Steps
2-Cyano-5-chlorophenol (3.0 g), epichlorohydrin (6.0 g) and anhydrous potassium carbonate (4.2 g) were heated with stirring in ethanol for 2 hours. The organic layer was concentrated under reduced pressure. The residue was purified by silica gel chromatography to give 3.1 g of 1-(2-cyano-5-chlorophenoxy)-2,3-epoxypropane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04843072 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-63c840fbf5484efbba50b63b37a9a6cc |
| Source note | uspto-grants-1989_06 |