2-Fluoro-4-(1,1,2,2-tetrafluoroethanesulfinyl)aniline → HCID 13578905, compound

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Reaction Steps

To a solution of 0.7 g of 2-fluoro-4-(1,1,2,2-tetrafluoroethylsulfinyl)aniline in 15 ml of toluene was added 0.5 g of 2-fluoro-6-chlorobenzoyl isocyanate. After the reaction was allowed to proceed at room temperature (20° to 25° C.) for 30 minutes, the crystals which separated out were recovered by filtration and washed with toluene to give 1.0 g of N-(2-fluoro-6-chlorobenzoyl)-N'-[2-fluoro-4-(1,1,2,2-tetrafluoroethylsulfinyl)phenyl]urea (Compound No. 31), m.p. of 213°-216° C.

Provenance & Evidence