HCID 19835155, compound → HCID 19835170, compound

HRID 1905454Notes

Reaction equation

HRID 1905454 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]1[C:19]2[C:14](=[C:15]([OH:20])[CH:16]=[CH:17][CH:18]=2)[C:13](=[O:21])[C:12]2[C:11]([OH:22])=[CH:10][CH:9]=[CH:8][C:7]1=2>C(OC(=O)C)(=O)C.N1C=CC=CC=1>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[C:19]2[C:14](=[C:15]([O:20][C:15](=[O:20])[CH3:14])[CH:16]=[CH:17][CH:18]=2)[C:13]([O:21][C:13](=[O:21])[CH3:12])=[C:12]2[C:7]=1[CH:8]=[CH:9][CH:10]=[C:11]2[O:22][C:11](=[O:22])[CH3:10]

Participants

4

Reactant 1

HCID 19835155HCID 19835155, compound

Product 1

HCID 19835170HCID 19835170, compoundYield 170.3%

Reagents, catalysts & solvents 2

HCID 1049PyridineCatalystHCID 7918Acetic AnhydrideSolvent

Conditions

Temperature
80 °C

Procedure

In a three-necked flask equipped with a magnetic agitator, there are stirred 250 mg of 10-(2-thienyl)-1,8-dihydroxy anthrone, obtained according to example 8, in 5 cm3 of acetic anhydride and several drops of pyridine. The mixture is stirred for 3 hours at 80° C. under an inert atmosphere, then cooled. The expected triester crystallizes and is then filtered and washed with hexane, yielding 300 mg of light yellow crystals having a melting point of 260° C.

Workup

  1. customIn a three-necked flask equipped with a magnetic agitator, there
  2. customobtained
  3. temperaturecooled
  4. customThe expected triester crystallizes
  5. filtrationis then filtered
  6. washwashed with hexane

Sources & evidence

ORD record
ord-8fe035f6f61c4e79a4f510bafd5cbff2
Source dataset
uspto-grants-1989_06
Patent number
US04843097

Reaction notes

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