HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → Ethyl 3-anilinobut-2-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Ethyl 3-anilinobut-2-enoate | HCID 94928 | — |
Reaction Steps
Aniline (0.20 mol) and ethylacetoacetate (0.20 mol) are mixed in toluene (200 mL) containing 0.04 g of p-toluenesulfonic acid-hydrate and heated at reflux under a water separator for one hour. The toluene is removed under vacuum to afford the ethyl-3-phenylaminobut-2-enoate which can be used as is for the preparation of the ethyl 2-methyl-3-quinolinecarboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04843162 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-11982e9c5a8d4772857de0cb0a12a71c |
| Source note | uspto-grants-1989_06 |