HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → N-(3-Amino-2-oxoazetidin-3-yl)-2-phenoxyacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 20162854 | HCID 20162854 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(3-Amino-2-oxoazetidin-3-yl)-2-phenoxyacetamide | HCID 20193893 | — |
Reaction Steps
The sulphoxide (26) (186 mg) in dry tetrahydrofuran (6 ml) was treated with dry ammonia gas (14.8 ml) and the mixture stirred at room temperature for 3 days. The solvent was evaporated and the residue chromatographed on silica gel to give the product, (27) (113 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04647558 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-2e7f3a9433ff41fc8155df2b3a25c3a1 |
| Source note | uspto-grants-1987_03 |