HCID 152428, compound → HCID 20215478, compound

HRID 1905815Notes

Reaction equation

HRID 1905815 reaction equation
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][CH:14]=[CH:13][C:4]=1[CH:5]=[C:6]1[NH:10][C:9](=[O:11])[NH:8][C:7]1=[O:12]>[OH-].[Na+].[Ni]>[CH3:1][O:2][C:3]1[CH:16]=[CH:15][CH:14]=[CH:13][C:4]=1[CH2:5][CH:6]1[NH:10][C:9](=[O:11])[NH:8][C:7]1=[O:12]

Participants

4

Reactant 1

HCID 152428HCID 152428, compound

Product 1

HCID 20215478HCID 20215478, compoundYield 79%

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 14798Sodium HydroxideSolvent

Procedure

218.2 g (1 mole) of 5-(2-methoxy-benzylidene)-hydantoin are dissolved in 2 l of a N sodium hydroxide solution and 70 g of wet Raney-nickel are added. The reaction mixture is worked up according to Example 6. Thus 174 g of the desired compound are obtained, yield 79%. Mp.: 186° C.

Workup

  1. additionare added

Sources & evidence

ORD record
ord-46c5f07967c648d2a445a0896e668f89
Source dataset
uspto-grants-1987_03
Patent number
US04647694

Reaction notes

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