HCID 275570, compound → HCID 20215477, compound

HRID 1905817Notes

Reaction equation

HRID 1905817 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:14]=[C:15]([O:19][CH3:20])[C:16]=1[O:17][CH3:18])[CH:6]=[C:7]1[NH:11][C:10](=[O:12])[NH:9][C:8]1=[O:13]>[OH-].[Na+].[Ni]>[CH3:20][O:19][C:15]1[CH:14]=[C:5]([CH:4]=[C:3]([O:2][CH3:1])[C:16]=1[O:17][CH3:18])[CH2:6][CH:7]1[NH:11][C:10](=[O:12])[NH:9][C:8]1=[O:13]

Participants

4

Reactant 1

HCID 275570HCID 275570, compound

Product 1

HCID 20215477HCID 20215477, compoundYield 78%

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 14798Sodium HydroxideSolvent

Procedure

278.3 g (1 mole) of 5-(3,4,5-trimethoxy-benzylidene)-hydantoin are dissolved in 2 l of a N sodium hydroxide solution and 40 g of wet Raney-nickel are added. The reaction mixture is worked up according to Example 6. Thus 218.6 g of the desired compound are obtained, yield 78%. Mp.: 180°-181° C.

Workup

  1. additionare added

Sources & evidence

ORD record
ord-6efe4a0d82364108bd258c73ae001185
Source dataset
uspto-grants-1987_03
Patent number
US04647694

Reaction notes

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