Triethylamine → HCID 13608188, compound

Participants

Reaction Steps

To a solution of 3,4-dihydro-6-(3-amino-4-methoxyphenyl)-1,3-dimethyl-4-(2,4,6-trimethylphenylimino)-2(1H)-pyrimidinone (0.39 g) in 1,2-dichloroethane (5 ml) were added methanesulfonyl chloride (0.40 ml) and triethylamine (0.52 ml) successively, and the mixture was refluxed for 2.5 hours. After cooling, the reaction mixture was dissolved in chloroform, and washed with water. The organic layer was dried over magnesium sulfate, evaporated, and crystallized from ethanol to give 3,4-dihydro-6-[3-(dimethanesulfonylamino)-4methoxyphenyl]-1,3-dimethyl-4-(2,4,6-trimethylphenylimino)-2-(1H)-pyrimidinone (0.33 g).

Provenance & Evidence