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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1905902Generated: October 30, 2026

Ethyl formate → Ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate

https://huagongshe.com/reaction/1905902

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl formateHCID 8025—
ReactantSodium hydrideHCID 24758—
ReactantEthyl 3-(6-methyl-3-pyridyl)propionateHCID 3018102—
Solvent1,2-DimethoxyethaneHCID 8071—
ProductEthyl 2-formyl-3-(6-methyl-3-pyridyl)propionateHCID 3018359—

Reaction Steps

Ethyl 3-(6-methyl-3-pyridyl)propionate was formylated with ethyl formate and sodium hydride in 1,2-dimethoxyethane to give ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate m.p. 142°-144°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04649141
Source datasetuspto-grants-1987_03
ORD IDord-ab9356521ba8446ca9e2f7c80af66dbd
Source noteuspto-grants-1987_03