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HRID1905909

反应详情

EQUATION

反应方程式

HRID 1905909 的结构方程式

REACTANTS

反应物

2
结构：CN(C)Cc1ccc(CSCCN)o1
HCID162203

5-((2-Aminoethyl)thiomethyl)-N,N-dimethyl-2-furanmethanamine

C10H18N2OS

结构：CSc1ncc(C(C)c2cccnc2)c(=O)[nH]1
HCID13505309

未命名化合物

PRODUCTS

生成物

1
结构：CC(c1cccnc1)c1cnc(NCCSCc2ccc(CN(C)C)o2)[nH]c1=O
HCID20213276

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

Equimolar amounts of 2-methylthio-5-[1-(3-pyridyl)ethyl]-4-pyrimidone and 2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamine in pyridine are boiled under reflux for 48 hours and evaporated to dryness. The residue is purified to give 2-[2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-(1-(3-pyridyl)ethyl)-4-pyrimidone.

WORKUP

后处理

  1. temperatureunder reflux for 48 hours
  2. customevaporated to dryness
  3. customThe residue is purified