HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylbenzenethiol → HCID 13456039, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylbenzenethiol | HCID 7811 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile | HCID 2733849 | — |
| Reactant | Potassium | HCID 5462222 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 13456039 | HCID 13456039 | — |
Reaction Steps
2,6-Dichloro-5-fluoronicotinonitrile (32.5 g) in ethanol (400 ml) was treated at room temperature with potassium salt of p-thiocresol, prepared from p-thiocresol (23.2 g) and potassium hydroxide (12.2 g), to give 2-chloro-6-(p-tolylthio)-5-fluoronicotinonitrile (42.4 g), m.p. 124°-125° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04649144 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-56dbf36c1ff84f2bbf8a9fc2abd8a882 |
| Source note | uspto-grants-1987_03 |