Acetic Anhydride → HCID 178474423, compound

HRID 1905937Notes

Reaction equation

HRID 1905937 reaction equation
[NH2:1][C:2]1[NH:3][CH:4]=[C:5]([C:7]2[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][CH:8]=2)[N:6]=1.[C:16](OC(=O)C)(=[O:18])[CH3:17]>>[C:16]([NH:1][C:2]1[NH:3][CH:4]=[C:5]([C:7]2[CH:8]=[CH:9][C:10]([N+:13]([O-:15])=[O:14])=[CH:11][CH:12]=2)[N:6]=1)(=[O:18])[CH3:17]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 178508304HCID 178508304, compound

Product 1

HCID 178474423HCID 178474423, compound

Conditions

Temperature
100 °C

Procedure

A mixture of 2-amino-4-(4-nitro-phenyl)-1H-imidazole (17.3 g) and acetic anhydride (100 ml) was heated at 100° C. for one hour. The resulting solution was evaporated to dryness, and the residue was treated with ether, filtered off and dried to give 18.9 g of the title compound.

Workup

  1. customThe resulting solution was evaporated to dryness
  2. additionthe residue was treated with ether
  3. filtrationfiltered off
  4. customdried

Sources & evidence

ORD record
ord-e6bb1a6c3a0f4300a80c7786e5a1ea38
Source dataset
uspto-grants-1987_03
Patent number
US04649150

Reaction notes

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