Sulfuric Acid → HCID 178432558, compound

Participants

Reaction Conditions

Reaction Steps

2-Methyl-4-(3-methyl-phenyl)-1H-imidazole nitrate (15 g) was added portionwise to 96% sulfuric acid (40 ml) at room temperature. The resulting solution was heated at 90° C. for one hour, cooled, diluted with water (200 ml) and neutralized with aqueous sodium carbonate. The solid which separated out was filtered off, and the filtrate was made strongly alkaline with 10% sodium hydroxide. The base which precipitated was filtered off and dried to give 5 g of the title compound sufficiently pure to be used in the next step.

Provenance & Evidence