Methanesulfonyl chloride → HCID 13208942, compound

HRID 1905967Notes

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][O:10][CH2:11][CH2:12][OH:13])=[CH:4][CH:3]=1.[CH3:14][S:15](Cl)(=[O:17])=[O:16]>>[CH3:14][S:15]([O:13][CH2:12][CH2:11][O:10][CH2:9][CH2:8][C:5]1[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=1)(=[O:17])=[O:16]

Participants

Reactant 2

HCID 31297Methanesulfonyl chloride

HCID 13208930HCID 13208930, compound

Product 1

HCID 13208942HCID 13208942, compoundYield 87%

Procedure

The 2-[2-(4-fluorophenyl)ethoxy]ethanol obtained according to the preceding paragraph was sulfonylated with methanesulfonyl chloride in a manner analogous to that described in Example 1(c) to give 8.2 g (87%) of 2-[2-(4-fluorophenyl)ethoxy]ethyl methanesulfonate in the form of an oil which was homogeneous according to chromatography.

Sources & evidence

ORD record: ord-fbc0bf5fcac74b00923245a4402dc2e8
Source dataset: uspto-grants-1987_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04649160

Reaction notes

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