Methanesulfonyl chloride → 2-[2-(4-Chlorophenyl)ethoxy]ethyl methanesulfonate

HRID 1905982Notes

Reaction equation

HRID 1905982 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][O:10][CH2:11][CH2:12][OH:13])=[CH:4][CH:3]=1.[CH3:14][S:15](Cl)(=[O:17])=[O:16]>>[CH3:14][S:15]([O:13][CH2:12][CH2:11][O:10][CH2:9][CH2:8][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=1)(=[O:17])=[O:16]

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 132089322-[2-(4-Chlorophenyl)ethoxy]ethanol

Product 1

HCID 132108222-[2-(4-Chlorophenyl)ethoxy]ethyl methanesulfonateYield 92%

Procedure

The 2-[2-(4-chlorophenyl)ethoxy]ethanol obtained according to the preceding paragraph was sulfonylated with methanesulfonyl chloride in a manner analogous to that described in Example 1(c) to give 1.5 g (92%) of 2-[2-(4-chlorophenyl)ethoxy]ethyl methanesulfonate in the form of an oil which was homogeneous according to chromatography.

Sources & evidence

ORD record
ord-84d926e077234aa0a7ee534152bcf001
Source dataset
uspto-grants-1987_03
Patent number
US04649160

Reaction notes

Loading…