Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) → HCID 13563080, compound

Participants

Reaction Conditions

Reaction Steps

In 80 ml of ethanol was dissolved 4.17 g (9.4 mmoles) of the above tetrahydropyranyl ether (3), and 248 mg (0.98 mmoles) of pyridinium p-toluenesulfonate was added. The mixture was stirred at 55° C. for 3 hours. The solvent was distilled off under reduced pressure and the residue was subjected to silica gel chromatography [eluent: n-hexane-ethyl acetate (2:1)] to give 2.9 g (86%) of the desired compound as a colorless wax.

Provenance & Evidence