Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1,4-Bis(bromomethyl)benzene | HCID 69335 | — |
| Reactant | N-tert-butylhydroxylamine hydrochloride | HCID 2777896 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 13827671 | HCID 13827671 | 62.8% |
Reaction Steps
A suspension of 3.0 g tert-butylhydroxylamine hydrochloride, 5.0 g of anhydrous sodium carbonate and 3.15 g of p-xylylene dibromide in 20 ml of N,N-dimethylformamide is heated at 80° C. under nitrogen for 3 hours. Dilution of the reaction mixture with water followed by crystallization from heptane affords 2.1 g of product as a white solid; m.p. 137°-138° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04649221 |
|---|
| Source dataset | uspto-grants-1987_03 |
|---|
| ORD ID | ord-946f05c2ba2f47af88ab52b9d1d9fdc6 |
|---|
| Source note | uspto-grants-1987_03 |
|---|
