tert-Butoxy bis(dimethylamino)methane → HCID 131714508, compound

Participants

Reaction Steps

C-2. 6-[2-(Dimethylamino)ethenyl]-5-(2-thienylcarbonyl)-2(1H)-pyridinone--To a mixture containing 57.8 g of 6-methyl-5-(2-thienylcarbonyl)-2(1H)-pyridinone in 400 ml of p-dioxane was added with stirring 62 g of bis(dimethylamino)-t-butoxymethane and the resulting reaction mixture was heated on a steam bath for 2 and 1/2 hours and then cooled. The separated product was collected, washed with isopropyl alcohol, dried in a vacuum oven at 90° C. to yield 70.1 g of 6-[2-dimethylamino)ethenyl]-5-(2-thienylcarbonyl)-2(1H)-pyridinone, m.p. 248°-250° C.

Provenance & Evidence