Hydrazine hydrate (1:1) → HCID 13728032, compound

Participants

Reaction Conditions

Reaction Steps

In 50 ml of isopropylalcohol was dissolved 6.4 g of 3-octadecyloxy-2-phthalimido-1-trityloxypropane, and 4 ml of hydrazine hydrate was added to the solution. The mixture was heated at 70° C. for 1 hour, and concentrated under reduced pressure. Ethyl acetate was added to the residue and the insoluble matter was filtered off. The filtrate was concentrated to dryness and purified by silica gel chromatography (eluent: n-hexane-ethyl acetate=3:1) to give 4.41 g (84%) of the desired compound as a pale brown solid.

Provenance & Evidence