HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Nitrophenyl)propanamide → 4-Aminophenyl propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Nitrophenyl)propanamide | HCID 5086405 | — |
| Catalyst | Palladium monoxide | HCID 5083724 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Aminophenyl propionamide | HCID 12805228 | 100.4% |
Reaction Steps
2-(4-Nitrophenyl)propionamide (5.3 g) in ethanol (250 ml) was hydrogenated over palladium oxide on charcoal (5%, 0.5 g) at atmospheric pressure. The reaction was terminated after 1775 ml of hydrogen had been absorbed and the catalyst was removed by filtration. Removal of the solvent gave the title compound as a white solid (4.5 g), m.p. 120°-122°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04650810 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-ad9a60c6c407446da177feb7fca04fac |
| Source note | uspto-grants-1987_03 |