HCID 12805220, compound → HCID 12805213, compound

HRID 1906234Notes

Reaction equation

HRID 1906234 reaction equation
[O:1]=[C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:11])[N:3]1[CH2:12][CH2:13][C:14]1[C:22]2[C:17](=[CH:18][CH:19]=[C:20]([CH2:23][C:24]#[N:25])[CH:21]=2)[NH:16][CH:15]=1.C[OH:27].C(Cl)Cl>>[O:11]=[C:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[C:2](=[O:1])[N:3]1[CH2:12][CH2:13][C:14]1[C:22]2[C:17](=[CH:18][CH:19]=[C:20]([CH2:23][C:24]([NH2:25])=[O:27])[CH:21]=2)[NH:16][CH:15]=1

Participants

3

Reactant 2

HCID 12805220HCID 12805220, compoundHCID 21226129Dichloromethane methanol

Product 1

HCID 12805213HCID 12805213, compound

Procedure

TLC Polygram silica, 5% methanol/methylene chloride showed a single new product with Rf 0.13 identical with that of a sample prepared by the method of Example 2 (ii).

Sources & evidence

ORD record
ord-ebba714b4dfe4a29abd3212e968147d5
Source dataset
uspto-grants-1987_03
Patent number
US04650810

Reaction notes

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