HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Pyrrolidineacetamide, 3-hydroxy-2-oxo-, (+-)- → 1-Pyrrolidineacetamide, 3-hydroxy-2-oxo-, (S)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Pyrrolidineacetamide, 3-hydroxy-2-oxo-, (+-)- | HCID 3069854 | — |
| Reactant | ethyl (S)-(-)-2-(3-hydroxy-1-pyrrolidinyl)acetate | HCID 54107293 | — |
| Product | 1-Pyrrolidineacetamide, 3-hydroxy-2-oxo-, (S)- | HCID 3069834 | — |
Reaction Steps
According to the process described in paragraph (b) of Example 1, from ethyl (S)-(-)-2-(3-hydroxy-1-pyrrolidinyl)acetate there is obtained (S)-(-)-2-(3-hydroxy-2-oxo-1-pyrrolidinyl)acetamide which has a melting point of 197°--198°; [α]D20 =-82°, [α]54620 =-99°, [α]36520 =-313° (dimethylformamide c=1.00).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04650878 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-10d0a99bc0ca46fba1ffaf45a39f49e5 |
| Source note | uspto-grants-1987_03 |