O-ethylhydroxylamine hydrochloride → HCID 136332183, compound

HRID 1906353Notes

Reaction equation

HRID 1906353 reaction equation
[OH:1][C:2]1[CH2:7][CH:6]([C:8]2[C:13]([CH3:14])=[CH:12][C:11]([CH3:15])=[C:10]([C:16](=[S:18])[NH2:17])[C:9]=2[CH3:19])[CH2:5][C:4](=[O:20])[C:3]=1[C:21](=O)[CH2:22][CH3:23].Cl.[CH2:26]([O:28][NH2:29])[CH3:27]>>[CH2:26]([O:28][N:29]=[C:21]([C:3]1[C:4](=[O:20])[CH2:5][CH:6]([C:8]2[C:13]([CH3:14])=[CH:12][C:11]([CH3:15])=[C:10]([C:16](=[S:18])[NH2:17])[C:9]=2[CH3:19])[CH2:7][C:2]=1[OH:1])[CH2:22][CH3:23])[CH3:27]

Participants

3

Reactant 2

HCID 76850O-ethylhydroxylamine hydrochlorideHCID 178458840HCID 178458840, compound

Product 1

HCID 136332183HCID 136332183, compound

Procedure

The reaction of 3-hydroxy-5-(3-thiocarbamoyl-2,4,6-trimethylphenyl)-2-propionylcyclohex-2-en-1-one with ethoxyamine hydrochloride was carried out following the same procedure as that described in Example 1 part (v) to give 2-[1-(ethoxyimino)propyl]-3-hydroxy-5-(3-thiocarbamoyl-2,4,6-trimethylphenyl)cyclohex-2-en-1-one (24) as a tan oil. The compound was characterized by its proton nuclear magnetic resonance spectrum and the data are recorded in Table 3, Example 11.

Sources & evidence

ORD record
ord-f21176fba24e4788b23e684010488c9d
Source dataset
uspto-grants-1987_03
Patent number
US04652303

Reaction notes

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