Water → HCID 86741353, compound

Participants

Reaction Steps

To a stirred mixture of 3.9 g (0.02 mole) 2-methyl-2-(ethenylsulfonamido)propionitrile (the product of Example 22), 5.0 g (0.02 mole) 1,1,2,2-tetrachloroethylsulfenyl chloride and 0.5 g benzyltriethylammonium chloride in 150 ml methylene chloride, cooled by an ice bath, 10 ml water was added; then 1.6 g (0.02 moles) 50% sodium hydroxide was added dropwise. The reaction mixture was stirred and allowed to come to room temperature overnight. The reaction mixture was washed twice with equal amounts (about 150 ml) water, dried over magnesium sulfate, filtered and stripped. The solid residue was washed with petroleum ether and then dried to give 3.3 g of the above-identified product as a beige solid.

Provenance & Evidence