反应详情

To a stirred mixture of 90.5 g (0.44 moles) sodium 2-carboethoxyethyl sulfonate (the product of Example 26) in 300 ml chloroform, 92 g (0.44 moles) phosphorus pentachloride was added in small portions, maintaining the temperature of the reaction mixture below 40° C. during the addition. The reaction mixture was refluxed for about 6 hours, and then filtered. Nitrogen was bubbled through the solution to remove excess hydrogen chloride gas. Stripping of the solvent gave 28.4 g of the above-identified product.

1. temperaturemaintaining the temperature of the reaction mixture below 40° C.
2. additionduring the addition
3. temperatureThe reaction mixture was refluxed for about 6 hours
4. filtrationfiltered
5. customNitrogen was bubbled through the solution
6. customto remove excess hydrogen chloride gas