Ammonium Hydroxide → HCID 18607003, compound

Participants

Reaction Steps

A sample of the above hydrochloride, in water was treated with concentrated ammonium hydroxide and the aqueous suspension was extracted with ether. The ether solutions were washed with water and dried (magnesium sulfate). Removal of the solvent gave the base, which after crystallization from ether afforded (±)-cis-3-(acetyloxy)-5-[2-(diethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)naphtho[1,2-b]-1,4-thiazepin-4(5H)-one, mp 148°-149°.

Provenance & Evidence